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. 2022 Apr 9;22:385. doi: 10.1186/s12885-022-09454-y

Table 2.

Associations of age (years) at diagnosis with palliative therapy in patients with recurrent metastatic breast cancer from a breast cancer cohort in China between 1989 and 2020

All < 40 40–64 ≥ 65 P
Regimens
No. ( %) No. (%) No. ( %) No. ( %)
Palliative chemotherapy < 0.001
 No/ unknown 746 (45.60) 148 (40.77) 533 (45.44) 65 (65.00)
 Yes 890 (54.40) 215 (59.23) 640 (54.56) 35 (35.00)
Palliative radiotherapy 0.259
 No/ unknown 1,437 (87.84) 311 (85.67) 1,035 (88.24) 91 (91.00)
 Yes 199 (12.16) 215 (59.23) 138 (11.76) 9 (9.00)
Palliative hormonal therapy 0.013
 No/ unknown 1,055 (64.49) 212 (58.40) 772 (65.81) 71 (71.00)
 Yes 581 (35.51) 151 (41.60) 401 (34.19) 29 (29.00)
Palliative target therapy 0.077
 No/ unknown 1,494 (91.32) 326 (89.81) 1,071 (91.30) 97 (97.00)
 Yes 142 (8.68) 37 (10.19) 102 (8.70) 3 (3.00)
No. of regimens 0.003
 One 577 (35.27) 122 (33.61) 418 (35.64) 37 (37.00)
 Tow 375 (22.92) 102 (28.1) 261 (22.25) 12 (12.00)
 Three 147 (8.99) 39 (10.74) 103 (8.78) 5 (5.00)
 Four 11 (0.67) 3 (0.83) 8 (0.68) 0 (0.00)
 Unknown 526 (32.15) 97 (26.72) 383 (32.65) 46 (46.00)
One regimen 0.125
 Only chemotherapy 374 (64.82) 76 (62.29) 278 (66.51) 20 (54.05)
 Only radiotherapy 13 (2.25) 2 (1.64) 8 (1.91) 3 (8.11)
 Only hormonal therapy 183 (31.72) 41 (33.61) 128 (30.62) 14 (37.84)
 Only target therapy 7 (1.21) 3 (2.46) 4 (0.96) 0 (0.00)
Two regimens 0.190
 Chemo- and radiotherapy 60 (16.00) 17 (16.67) 42 (16.09) 1 (8.33)
 Chemo- and hormonal 239 (63.73) 65 (63.73) 166 (63.60) 8 (66.67)
 Chemo- and target 59 (15.73) 15 (14.71) 43 (16.48) 1 (8.33)
 Radiotherapy and hormonal 10 (2.67) 2 (1.96) 6 (2.30) 2 (16.67)
 Radiotherapy and target 0 (0.00) 0 (0.00) 0 (0.00) 0 (0.00)
 Hormonal and target 7 (1.87) 3 (2.94) 4 (1.53) 0 (0.00)