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Schematic of a synapse showing the production of noradrenaline (from L‐DOPA) and its release across the synapse. Also, the reuptake and degradation of noradrenaline by COMT and MAO enzymes. Also shown are the key adrenergic receptors upon which it acts and the site of action of some key classes of drugs. DA, dopamine; NE, noradrenaline/norepinephrine; NET, norepinephrine transporter; L‐DOPA, levodopa; MAO, monoamine oxidase; COMT, catechol‐o‐methyltransferase.
