Table 3.
Multivariate Logistic Regression Analysis for Selected Perioperative Parameters Predicting Delirium
| Variable | OR | 95% CI | P value | |
|---|---|---|---|---|
| Model 1 | Age | 1.066 | 0.990–1.148 | 0.092 |
| Stroke | 0.712 | 0.197–2.576 | 0.605 | |
| Operation site | 0.353 | 0.058–2.158 | 0.260 | |
| Operation time | 1.100 | 0.500–2.422 | 0.813 | |
| Bleeding | 1.004 | 0.996–1.011 | 0.360 | |
| Benzodiazepines | 7.912 | 1.884–33.230 | 0.005 | |
| Change of CRP | 1.017 | 1.007–1.027 | 0.001 | |
| Preoperative NLR | 0.970 | 0.593–1.588 | 0.905 | |
| Preoperative PLR | 0.989 | 0.973–1.006 | 0.218 | |
| Preoperative PWR | 1.022 | 0.929–1.123 | 0.658 | |
| Postoperative NLR | 1.358 | 1.012–1.823 | 0.041 | |
| Postoperative PLR | 1.003 | 0.991–1.015 | 0.631 | |
| Postoperative PWR | 1.028 | 0.914–1.156 | 0.644 | |
| Omnibus test of model coefficients p<0.001 | ||||
| Hosmer and Lemeshow test p=0.435 | ||||
| Model 2 | Age | 1.073 | 1.001–1.149 | 0.046 |
| Stroke | 0.780 | 0.229–2.649 | 0.690 | |
| Operation site | 0.492 | 0.089–2.726 | 0.417 | |
| Operation time | 0.996 | 0.469–2.118 | 0.992 | |
| Bleeding | 1.005 | 0.997–1.012 | 0.204 | |
| Benzodiazepines | 6.811 | 1.652–28.081 | 0.008 | |
| Change of CRP | 1.015 | 1.006–1.023 | 0.001 | |
| Change of NLR | 1.266 | 1.035–1.549 | 0.022 | |
| Change of PLR | 1.004 | 0.994–1.013 | 0.425 | |
| Change of PWR | 1.014 | 0.952–1.080 | 0.667 | |
| Omnibus test of model coefficients p<0.001 | ||||
| Hosmer and Lemeshow test p=0.392 | ||||
Note: Bold indicates P-values less than 0.05.
Abbreviations: OR, odds ratio; CI, confidence interval; CRP, c-reactive protein; NLR, neutrophil-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; PWR, platelet-to-WBC ratio; AUC, area under the curve.