Table 2.
Top 20 upregulated Cancer Census genes in pegvisomant-treated PTEN-CaP2 xenografts
| Gene symbol | Gene name | Log2 fold change | Corrected P |
|---|---|---|---|
| Klk1 | Kallikrein 1 | 4.231 | 9.819 × 10–30 |
| Ptprd | Protein tyrosine phosphatase, receptor type, D | 4.131 | 1.768 × 10-8 |
| A1cf | APOBEC1 complementation factor | 3.975 | 7.557 × 10–20 |
| Hnf1a | HNF1 homeobox A | 3.502 | 5.789 × 10–9 |
| Nrg1 | Neuregulin 1 | 3.389 | 3.409 × 10–9 |
| Omd | Osteomodulin | 3.170 | 1.396 × 10–7 |
| Gli1 | GLI-Kruppel family member GLI1 | 3.107 | 4.820 × 10–9 |
| Creb3l1 | cAMP responsive element binding protein 3-like 1 | 3.059 | 4.950 × 10−4 |
| Pax8 | Paired box 8 | 3.013 | 1.611 × 10−3 |
| Bcl11b | B-cell leukemia/lymphoma 11B | 2.973 | 4.048 × 10−3 |
| Hoxc13 | Homeobox C13 | 2.807 | 1.011 × 10−3 |
| Map3k13 | Mitogen-activated protein kinase kinase kinase 13 | 2.779 | 3.061 × 10–9 |
| Il7r | Interleukin 7 receptor | 2.735 | 6.567 × 10−4 |
| Cblc | Casitas B-lineage lymphoma c | 2.719 | 1.056 × 10−3 |
| Tmprss2 | Transmembrane protease, serine 2 | 2.582 | 4.774 × 10–9 |
| Hlf | Hepatic leukemia factor | 2.551 | 1.679 × 10−3 |
| Prdm16 | PR-domain containing 16 | 2.542 | 9.043 × 10−3 |
| Mn1 | Meningioma 1 | 2.454 | 5.333 × 10−4 |
| Cdh1 | Cadherin 1 | 2.435 | 1.258 × 10−3 |
| Esr1 | Estrogen receptor 1 (α) | 2.378 | 5.514 × 10−5 |