Table 1.
Baseline and cycle characteristics in women with and without endometriosis
| Factor | Total (N = 434) | No endometriosis (N = 286) | Endometriosis (N = 148) | p value |
|---|---|---|---|---|
| Age (years) | 33.2 ± 3.8 | 33.0 ± 3.8 | 33.7 ± 3.7 | 0.042a1 |
| BMI (kg/m2) | 26.0 ± 6.1 | 25.8 ± 6.2 | 26.5 ± 5.9 | 0.27a1 |
| AMH (ng/mL) | 2.0 [1.2, 3.8] | 2.3 [1.4, 4.2] | 1.5 [0.77, 3.1] | < 0.001b |
| Gravity | 0.00 [0.00, 1.00] | 0.00 [0.00, 1.00] | 0.00 [0.00, 1.00] | 0.065b |
| Parity | 0.00 [0.00, 0.00] | 0.00 [0.00, 1.00] | 0.00 [0.00, 0.00] | 0.003b |
| Race | 0.88d | |||
| White | 348 (82.7) | 228 (81.7) | 120 (84.5) | |
| Black | 16 (3.8) | 11 (3.9) | 5 (3.5) | |
| Asian | 51 (12.1) | 35 (12.5) | 16 (11.3) | |
| Multiracial | 6 (1.4) | 5 (1.8) | 1 (0.70) | |
| Ethnicity | 0.52d | |||
| Hispanic | 11 (2.6) | 6 (2.2) | 5 (3.5) | |
| Non-Hispanic | 409 (97.4) | 271 (97.8) | 138 (96.5) | |
| Smoker | 0.70c | |||
| Current | 13 (3.0) | 9 (3.2) | 4 (2.7) | |
| Former | 73 (16.9) | 45 (15.8) | 28 (18.9) | |
| Never | 347 (80.1) | 231 (81.1) | 116 (78.4) | |
| Total FSH dose (units) | 2475.0 [1800.0, 3600.0] | 2250.0 [1800.0, 3375.0] | 2850.0 [1912.5, 4275.0] | < 0.001b |
| Peak E2 (pg/mL) | 2195.0 [1532.5, 2757.0] | 2323.0 [1659.0, 2780.0] | 2033.0 [1329.0, 2690.0] | 0.004b |
| Total oocytes retrieved | 14.3 ± 8.2 | 15.2 ± 8.2 | 12.6 ± 8.0 | 0.001a1 |
| Mature eggs | 9.8 ± 5.6 | 10.5 ± 5.9 | 8.4 ± 4.8 | < 0.001a2 |
| Fertilization rate | 0.80 [0.67, 0.90] | 0.78 [0.63, 0.89] | 0.80 [0.67, 0.94] | 0.036b |
| PGT-A | 51 (11.7) | 34 (11.9) | 17 (11.5) | 1.0d |
Statistics presented as mean ± SD, median [P25, P75], N (column %). p values: a1 = t test, a2 = Satterthwaite t test, b = Wilcoxon rank sum test, c = Pearson’s chi-square test, d = Fisher’s exact test. Abbreviations are as follows: BMI, body mass index; E2, estradiol; FSH, follicle-stimulating hormone; PGT-A, preimplantation genetic testing for aneuploidy