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The effect of severe osteopenia and ginger on creatinine clearance and GFR in control (CTRL), combined model of osteoporosis (CMO) and osteoporotic treated rats with ZO (CMO + ZO) or with Clp (CMO + Clp). The data represent the mean ± SEM. Comparisons are made between two groups: Osteoporotic (CMO) versus control group (CTRL): *p < 0.05; **p < 0.01; Osteoporotic treated with ZO (CMO + ZO) or Clp (CMO + Clp) versus osteoporotic group (CMO): # p < 0.05; ## p < 0.01
