Table 4:
Risk Factors Associated with Associated with Cardiovascular Events
| Univanate analysis | Multivanate analysis | |||
|---|---|---|---|---|
| Variables | HR (95%CI) | p | HR (95%CI) | p |
| * RV-LS at baseline, per % | 0.92 (0.88–0.96) | <0.001 | 0.94 (0.90–0.98) | 0.01 |
| Annual change in RV-LS, per % | 1.16 (1.08–1.31) | 0.005 | 1.11 (1.07–1.22) | <0.001 |
| Age, per year | 1.05 (1.02–1.08) | 0.004 | 1.03 (1.01–1.05) | 0.003 |
| Male sex | 1.11 (1.03–1.37) | 0.01 | ||
| Complex CC-TGA | --- | --- | ||
| LV pacing | 1.08 (1.01–1.15) | 0.03 | ||
| CRT | --- | --- | ||
| Tricuspid valve surgery | --- | --- | ||
| Atrial fibrillation | --- | --- | ||
| Hypertension | 1.36 (1.12–2.81) | 0.004 | 1.49 (1.16–2.68) | 0.04 |
| ≥Moderate tricuspid regurgitation | --- | --- | ||
| Heart failure therapy | --- | --- | ||
CC-TGA: congenitally corrected transposition of great arteries; HR: hazard ratio CI: confidence interval; CRT: cardiac resynchronization therapy; LV: left ventricle; RV: right ventricle; LS: longitudinal strain
--- denoted variables with p≥0.25; Note that only variables with p<0.25 on univariable analysis were imputed into the multivariable model
*
note that LS was modeled as absolute values (i.e. ignoring the negative sign)