Why carry out this study?

The burden of psoriasis, particularly if impactful areas such as the scalp, nails, palms, and soles are affected, is very high

There were limited data available on dimethyl fumarate (DMF), an approved treatment for moderate-to-severe plaque psoriasis, in patients with psoriasis affecting impactful areas

The objective was to assess the long-term effectiveness and safety of DMF in patients with moderate-to-severe psoriasis, particularly those with involvement of impactful areas

What was learned from the study?

Long-term DMF treatment (until 52 weeks) showed good overall effectiveness and safety in routine practice

A positive effect on plaque-psoriasis-affected impactful areas, such as nails, palmoplantar area, and scalp, was shown as well