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. 2021 Jun 3;71(5):928–937. doi: 10.1136/gutjnl-2020-323219

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Effect of acute coadministration of 3′3 diindolylmethane (DIM), alpha linolenic acid and lauric acid (LA) on gut hormone levels in obese subjects. (A) Circulating levels of PYY were significantly increased in the active treatment compared with placebo. (B) GLP-1 levels did not significantly differ between active and placebo. (C) 5-HT levels did not significantly differ between active and placebo. (D) Ghrelin levels did not significantly differ between active and placebo. Capsules were given at time 0 and 5 hours, and breakfast was given at 1 hour and lunch given at 6 hours as indicated by arrows.