Table 4A.
Multiple logistic regression analysis of a strong decline of vaccination-specific anti-S1 IgG antibodies in seroconverted participants of the DIA-Vacc pure vaccination cohort between T2 and T3.
Table 4A. Strong IgG decline for all participants (n = 1205).
Risk factor | OR | 95% CI | p-value | OR, 95%CI (MICE) |
---|---|---|---|---|
Age | 1·007 | [0·998,1·016] | 0·142 | 1.008[1.007,1.009] |
Sex (Ref. = female) | 1·412 | [1·095,1·820] | 0·008 | 1.421[1.383,1.460] |
Vaccine type (Ref. = mRNA-1273) | 2·546 | [1·855,3·496] | <0·001 | 2.535[2.483,2.587] |
DP (Ref. = MP) | 3·237 | [1·897,5·525] | <0·001 | 2.953[2.766,3.153] |
KTR (Ref. = MP) | 1·926 | [1·018,3·644] | 0·044 | 1.702[1.615,1.793] |
Diabetes mellitus | 1·304 | [1·005,1·691] | 0·045 | 1.289[1.268,1.310] |
MP = Medical Personnel; DP = Dialysis Patients; KTR = Kidney Transplant Recipient; Ref. = reference category; a “strong IgG strong fading response antibody decline” between T2 (two months after first vaccination) and T3 (six months) was defined as described in Results and in more detail in Supplementary material. Comparator is the MP cohort. MICE means multiple imputation with chained equations.
Model fit: AIC = 1556.70; BIC = 1592.35.