Table 4C.
Risk factor | OR | 95% CI | p-value | OR,95%CI (MICE) |
---|---|---|---|---|
Age | 1·005 | [0·995,1·014] | 0·367 | 1.003[1.002,1.004] |
Sex (Ref. = female) | 1·445 | [1·089,1·916] | 0·011 | 1.421[1.401,1.442] |
Vaccine type (Ref. = mRNA-1273) | 2·684 | [1·836,3·923] | < 0·001 | 2.677[2.591,2.767] |
BMI | 0·990 | [0·967,1·014] | 0·428 | 0.988[0.986,0.990] |
IS drugs (Ref. = no drugs) | 3·052 | [1·360,6·849] | 0·007 | 3.340[3.107,3.590] |
Time on dialysis | 0·977 | [0·953,1·001] | 0·058 | 0.977[0.975,0.979] |
Hep B vacc failure (Ref. = no) | 1·002 | [0·723,1·388] | 0·990 | 0.965[0.945,0.986] |
Diabetes mellitus (Ref. = none) | 1·386 | [1·041,1·845] | 0·025 | 1.389[1.356,1.424] |
Ref. = reference category; a “strong IgG antibody declinestrong fading response” between T2 (two months after first vaccination) and T3 (six months) was defined as described in Results and in more detail in Supplementary material. Comparator is the MP cohort. IS means immunosuppressiveon; BMI means body mass index; Hep B vacc failure definition - patients with unsuccessful vaccination after at least four attempts. MICE means multiple imputation with chained equations.
Model fit: AIC = 1277.30; BIC = 1325.86.