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. 2022 Apr 11;50(6):1475–1481. doi: 10.1007/s15010-022-01817-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Correlation of antibody binding titer and ACE2-receptor binding inhibition over time among COVID-19-naïve, dually vaccinated individuals (a) and COVID-19 convalescents after a single booster dose (b) (data and linear regression line displayed). Associated Pearson r/Spearman's rho values are – 0.9463/− 0.6908 for COVID-19 convalescents 1 year after COVID-19, − 0.6245/− 0.8915 for COVID-19 convalescents after booster dose, − 0.9033/− 0.9224 for COVID-19 convalescents 6 months after booster dose, − 0.7255/− 0.5911 for COVID-19-naïves after the 1st vaccine dose, − 0.8958/− 0.9556 for COVID-19-naïves after the 2nd vaccine dose, and − 0.6900/− 0.6226 for COVID-19-naïves 6 months after the 2nd vaccine dose (all corresponding two-tailed p values of the correlations were p < 0.0001)