TABLE 5.

The top10 differentially expressed proteins between intracellular M.tb and extracellular M.tb.

Genes	Fold change	UNIPROT_URL	Annotation	Differential expression
Rv1498A	4.140093396	http://www.uniprot.org/uniprot/I6XY36	Uncharacterized protein	Up
rpsF	2.279103053	http://www.uniprot.org/uniprot/P9WH31	30S ribosomal protein S6	Up
Rv1405c	2.26984127	http://www.uniprot.org/uniprot/P9WLY7	Putative methyltransferase	Up
TB22.2	2.091614333	http://www.uniprot.org/uniprot/I6YF08	hypothetical protein	Up
Rv1928c	2.063829787	http://www.uniprot.org/uniprot/P95286	Short-chain dehydrogenase	Up
lppE	2.016712009	http://www.uniprot.org/uniprot/O07750	lipoprotein LppE	Up
Rv2466c	1.998148148	http://www.uniprot.org/uniprot/O53193	Uncharacterized protein	Up
PPE41	1.907282133	http://www.uniprot.org/uniprot/Q79FE1	PPE family protein PPE41	Up
fbpB	1.894904459	http://www.uniprot.org/uniprot/P9WQP1	diacylglycerol acyltransferase/mycolyltransferase Ag85B	Up
Rv1674c	1.893905192	http://www.uniprot.org/uniprot/O53921	Transcriptional regulatory protein	Up
hupB	0.348717035	http://www.uniprot.org/uniprot/P9WMK7	DNA-binding protein Hu	Down
nuoL	0.342380423	http://www.uniprot.org/uniprot/P9WIW1	NADH dehydrogenase subunit	Down
embA	0.320856727	http://www.uniprot.org/uniprot/P9WNL9	Arabinosyltransferase EmbA	Down
gadB	0.315456165	http://www.uniprot.org/uniprot/I6YG46	Glutamate decarboxylase GadB	Down
mmpL13b	0.29913522	http://www.uniprot.org/uniprot/O06546	Trehalose monomycolate RND transporter MmpL3	Down
Rv0338c	0.286153846	http://www.uniprot.org/uniprot/O33268	Iron sulfur–binding protein	Down
aftC	0.276993265	http://www.uniprot.org/uniprot/P9WMZ7	α-(1->3)-Arabinofuranosyltransferase	Down
qcrB	0.245286344	http://www.uniprot.org/uniprot/P9WP37	Ubiquinol-cytochrome C reductase cytochrome subunit B	Down
rpmF	0.235881842	http://www.uniprot.org/uniprot/P9WH99	50S ribosomal protein	Down
eccD3	0.219337979	http://www.uniprot.org/uniprot/P9WNQ3	ESX-3 secretion system protein EccD	Down