Table 1.
Summary of patient demographics, PFTs and 6MW parameters
| Overall cohort (n=89) | Subgroup with chest CT (n=26) |
|||
| Sex (M/F) | 60/29 | 18/8 | ||
| Age (years) | 71.7±7.8 | 72.9±6.3 | ||
| Height (cm) | 167.4±9.6 | 167.2±8.7 | ||
| Weight (kg) | 76.3±14.4 | 74.2±11.2 | ||
| BMI (kg/m2) | 27.2±4.2 | 26.5±3.4 | ||
| Smoking Status | ||||
| Never smoked | 34 | 8 | ||
| Ex-smoker <20 pk years | 28 | 10 | ||
| Ex-smoker ≥ 20 pk years | 27 | 8 | ||
| Absolute values | % predicted | Absolute values | % predicted | |
| FVC (L) | 2.6±0.8 | 70±17 | 2.6±0.8 | 71±16 |
| FEV1(L) | 2.1±0.6 | 74±18 | 2.1±0.7 | 76±18 |
| FEV1/FVC (%) | 80.2±5.5 | 106±7 | 80.3±6.2 | 106±9 |
| TLC (L) | 4.3±1.0* | 70±13* | 4.8±1.0 | 72±13 |
| RV (L) | 1.6±0.4* | 71±15* | 1.7±0.5 | 74±19 |
| RV/TLC (%) | 38.6±7.2* | 92±16* | 39.2±9.1 | 91±21 |
| DLCO (mL/min/mm Hg) | 10.9±3.8* | 62±17* | 11.0±3.6 | 62±15 |
| 6MW min O2 sat (%) | 87.7±7.1† | -- | 89.0±5.7 | -- |
| 6MW distance (m) | 453.8±101.4† | 103±22† | 460.1±82.5 | 107±18 |
Data are shown as mean±SD. The overall cohort and the subgroup were similar.
*n=74.
†6 patients walked with supplemental O2.
BMI, body mass index; DLCO, diffusing capacity for carbon monoxide; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; 6MW, 6-min walk; PFT, pulmonary function test; RV, residual volume; TLC, total lung capacity.