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. 2021 Nov 20;45(4):zsab276. doi: 10.1093/sleep/zsab276

Table 3.

Multivariable-adjusted ORs and 95% CIs of sleep outcomes by quartiles of magnesium intake levels stratified by depression status

Quartiles of magnesium intake (mg/1,000 kcal/day) P trend
Q1
(lowest)
Q2 Q3 Q4
(highest)
Outcome: sleep quality (ORs of better sleep quality score)
CES-D <16 1(Ref.) 1.13 (0.96, 1.32) 1.15 (0.95, 1.39) 1.30 (1.04, 1.63) 0.02
CES-D ≥16 1(Ref.) 0.81 (0.59, 1.11) 0.71 (0.48, 1.05) 0.79 (0.48, 1.29) 0.34
p interaction 0.005
Outcome: sleep duration (ORs compared to the reference group: 7–9 h)
CES-D<16 <7 h vs. ref 1(Ref.) 0.98 (0.81, 1.18) 0.73 (0.59, 0.91) 0.64 (0.49, 0.82) <0.0001
>9 h vs. ref 1(Ref.) 0.77 (0.42, 1.42) 0.62 (0.26, 1.47) 0.73 (0.27, 1.95) 0.39
CES-D≥16 <7 h vs. ref 1(Ref.) 1.02 (0.70, 1.49) 1.24 (0.77, 1.99) 0.66 (0.38, 1.15) 0.33
>9 h vs. ref 1(Ref.) 1.22 (0.45, 3.30) 1.86 (0.48, 7.18) 1.21 (0.20, 7.19) 0.68
p interaction 0.07 (<7 h)
0.14 (>9 h)

All models were constructed using general estimation equations with adjustment for covariates in Model 3, Table 2. P for trend and p for interaction were examined using the medians of magnesium quartiles for sleep quality and using the continuous variable of ranks of magnesium intake (1 to 4) for sleep duration.

Abbreviations: CI, confidence interval; CES-D, Center for Epidemiologic Studies Depression Scale; h, hours; OR, odds ratio; Q, quartile; ref, reference.