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. 2021 Nov 20;45(4):zsab276. doi: 10.1093/sleep/zsab276

Table 5.

Multivariable-adjusted ORs and 95% CIs of sleep outcomes by quartiles of calcium-to-magnesium ratio levels stratified by depression status

Quartiles of calcium-to-magnesium ratio P trend
Q1
(lowest)
Q2 Q3 Q4
(highest)
Outcome: sleep quality (ORs of better sleep quality score)
CES-D <16 1(Ref.) 1.00 (0.86, 1.16) 1.00 (0.86, 1.17) 0.99 (0.84, 1.17) 0.97
CES-D ≥16 1(Ref.) 0.96 (0.71, 1.30) 0.96 (0.69, 1.32) 1.09 (0.76, 1.54) 0.65
p interaction .91
Outcome: sleep duration (ORs compared to the reference group: 7–9 h)
CES-D <16 <7 hrs vs. ref 1(Ref.) 0.98 (0.83, 1.15) 1.00 (0.84, 1.18) 1.09 (0.91, 1.31) 0.29
>9 hrs vs. ref 1(Ref.) 1.03 (0.47, 2.25) 1.43 (0.68, 3.02) 2.49 (1.23, 5.01) 0.008
CES-D ≥16 <7 hrs vs. ref 1(Ref.) 1.21 (0.83, 1.77) 0.81 (0.54, 1.21) 1.22 (0.78, 1.90) 0.70
>9 hrs vs. ref 1(Ref.) 0.53 (0.18, 1.62) 0.70 (0.22, 2.18) 0.89 (0.25, 3.18) 0.92
p interaction 0.79 (<7 h)
0.16 (>9 h)

All models were constructed using general estimation equations with adjustment for covariates in model 3, Table 3. P for trend and p for interaction were examined using the medians of Ca:Mg quartiles for sleep quality and using the continuous variable of ranks of Ca:Mg (1 to 4) for sleep duration.

Abbreviations: Ca, calcium; CES-D, Center for Epidemiologic Studies Depression Scale; CI, confidence interval; h, hours; Mg, magnesium; OR, odds ratio; Q, quartile; ref, reference.