Table 5.
Multivariable-adjusted ORs and 95% CIs of sleep outcomes by quartiles of calcium-to-magnesium ratio levels stratified by depression status
| Quartiles of calcium-to-magnesium ratio | P trend | |||||
|---|---|---|---|---|---|---|
| Q1 (lowest) |
Q2 | Q3 | Q4 (highest) |
|||
| Outcome: sleep quality (ORs of better sleep quality score) | ||||||
| CES-D <16 | 1(Ref.) | 1.00 (0.86, 1.16) | 1.00 (0.86, 1.17) | 0.99 (0.84, 1.17) | 0.97 | |
| CES-D ≥16 | 1(Ref.) | 0.96 (0.71, 1.30) | 0.96 (0.69, 1.32) | 1.09 (0.76, 1.54) | 0.65 | |
| p interaction | .91 | |||||
| Outcome: sleep duration (ORs compared to the reference group: 7–9 h) | ||||||
| CES-D <16 | <7 hrs vs. ref | 1(Ref.) | 0.98 (0.83, 1.15) | 1.00 (0.84, 1.18) | 1.09 (0.91, 1.31) | 0.29 |
| >9 hrs vs. ref | 1(Ref.) | 1.03 (0.47, 2.25) | 1.43 (0.68, 3.02) | 2.49 (1.23, 5.01) | 0.008 | |
| CES-D ≥16 | <7 hrs vs. ref | 1(Ref.) | 1.21 (0.83, 1.77) | 0.81 (0.54, 1.21) | 1.22 (0.78, 1.90) | 0.70 |
| >9 hrs vs. ref | 1(Ref.) | 0.53 (0.18, 1.62) | 0.70 (0.22, 2.18) | 0.89 (0.25, 3.18) | 0.92 | |
| p interaction | 0.79 (<7 h) 0.16 (>9 h) |
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All models were constructed using general estimation equations with adjustment for covariates in model 3, Table 3. P for trend and p for interaction were examined using the medians of Ca:Mg quartiles for sleep quality and using the continuous variable of ranks of Ca:Mg (1 to 4) for sleep duration.
Abbreviations: Ca, calcium; CES-D, Center for Epidemiologic Studies Depression Scale; CI, confidence interval; h, hours; Mg, magnesium; OR, odds ratio; Q, quartile; ref, reference.