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. 2022 Mar 28;14:853029. doi: 10.3389/fnagi.2022.853029

TABLE 3.

Longitudinal changes in cognition in a PDCN subsample.

Visit 1 Visit 2 p
Montreal Cognitive Assessment (MoCA) 27.0 (2.5) 26.7 (3.0) 0.43 0.13
Attention and working memory
Adaptive Digit Ordering (DOT) 6.7 (1.9) 6.2 (2.7) 0.12 0.26
DKEFS Color + Word Naming (CWN) 21.9 (4.3) 20.9 (4.4) 0.08 0.29
Executive (DKEFS)
Category switching (accuracy) (SWA) 13.6 (2.9) 11.5 (5.0) 0.009 0.49
Color-Word Inhibition (CWINH) 59.2 (14.2) 64.1 (22.5) 0.04 0.39
Memory (long delay free recall)
California Verbal Learning Test 2 (CVLT) 9.5 (3.3) 8.8 (5.2) 0.26 0.18
Brief Visuospatial Memory Test-Revised (BVMT) 8.7 (2.5) 8.6 (3.0) 0.84 0.03
Visual cognition
Judgment of Line Orientation (JLOT) 25.4 (2.6) 24.3 (4.5) 0.08 0.31
Hooper Visual Organization HVOT) 25.7 (2.5) 24.2 (3.6) 0.006 0.52
Semantic language
Boston naming (BNT) 57.8 (2.6) 57.9 (3.0) 0.86 0.03
DKEFS Category Fluency (CAT) 43.9 (8.6) 38.8 (9.2) 0.001 0.60

Tabled values are raw score means (standard deviations) from a subsample of 40 PDCN participants. Longitudinal changes between baseline (Visit 1) and follow-up testing (Visit 2) were analyzed using paired t-tests with bias corrected accelerated bootstrapping (1,000 iterations). Follow-up testing occurred a mean of 24.5 months (SD = 3.4) post-baseline testing: Significant p values in bold.

DKEFS, Delis Kaplan Executive Function System.

±Cohen’s d.