TABLE 3.
Longitudinal changes in cognition in a PDCN subsample.
Visit 1 | Visit 2 | p | d± | |
Montreal Cognitive Assessment (MoCA) | 27.0 (2.5) | 26.7 (3.0) | 0.43 | 0.13 |
Attention and working memory | ||||
Adaptive Digit Ordering (DOT) | 6.7 (1.9) | 6.2 (2.7) | 0.12 | 0.26 |
DKEFS Color + Word Naming (CWN) | 21.9 (4.3) | 20.9 (4.4) | 0.08 | 0.29 |
Executive (DKEFS) | ||||
Category switching (accuracy) (SWA) | 13.6 (2.9) | 11.5 (5.0) | 0.009 | 0.49 |
Color-Word Inhibition (CWINH) | 59.2 (14.2) | 64.1 (22.5) | 0.04 | 0.39 |
Memory (long delay free recall) | ||||
California Verbal Learning Test 2 (CVLT) | 9.5 (3.3) | 8.8 (5.2) | 0.26 | 0.18 |
Brief Visuospatial Memory Test-Revised (BVMT) | 8.7 (2.5) | 8.6 (3.0) | 0.84 | 0.03 |
Visual cognition | ||||
Judgment of Line Orientation (JLOT) | 25.4 (2.6) | 24.3 (4.5) | 0.08 | 0.31 |
Hooper Visual Organization HVOT) | 25.7 (2.5) | 24.2 (3.6) | 0.006 | 0.52 |
Semantic language | ||||
Boston naming (BNT) | 57.8 (2.6) | 57.9 (3.0) | 0.86 | 0.03 |
DKEFS Category Fluency (CAT) | 43.9 (8.6) | 38.8 (9.2) | 0.001 | 0.60 |
Tabled values are raw score means (standard deviations) from a subsample of 40 PDCN participants. Longitudinal changes between baseline (Visit 1) and follow-up testing (Visit 2) were analyzed using paired t-tests with bias corrected accelerated bootstrapping (1,000 iterations). Follow-up testing occurred a mean of 24.5 months (SD = 3.4) post-baseline testing: Significant p values in bold.
DKEFS, Delis Kaplan Executive Function System.
±Cohen’s d.