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. 2022 Mar 28;13:791802. doi: 10.3389/fmicb.2022.791802

Scheme 1.

Scheme 1

Synthetic route toward the target compound Str7410. ɑReagents and conditions. (A) N-tert-butoxycarbonyl-1,2-ethylenediamine, K2CO3, MeCN, 65°C, and 63% yield; (B) trifluoroacetic acid, CH2Cl2, room temperature, and 100% yield; and (C) K2CO3, ethyl 2-bromoacetate, MeCN, 45°C, and 56% yield; (D) concentrated hydrochloric acid, 100°C, and 54% yield.