Table 3.
Minimal inhibitory concentration (MIC) and minimum biofilm inhibitory concentration (MBIC) of antibiotics toward planktonic and biofilm cells of Pseudomonas aeruginosa PAO1 alone or in co-culture with Staphylococcus aureus ATCC 25923.
| Antibiotic | PAO1 | Mixed species | ||
|---|---|---|---|---|
| Planktonic cells MIC (μg/ml) | Biofilm cells MBIC (μg/ml) | Planktonic cells MIC (μg/ml) | Biofilm cells MBIC (μg/ml) | |
| Tobramycin base | 2 | 8 | 2 | 8 |
| Ceftazidime | 1 | 2 | 8 | 8 |
| Amikacin | 4 | 16 | 4 | 16 |
| Colistin sulfate | 4 | 64 | >64 | >64 |
| Ciprofloxacin | 0.08 | 0.25 | 0.25 | 0.5 |
| Meropenem trihydrate | 0.25 | 8 | 0.5 | 8 |
Data were obtained from three replicate experiments, n = 3.