Table 4.
Reference intervals of creatinine and urea established by GMM and SOM with more radical outlier detection strategy
| Age Groups | GMM Partitioned LIS | SOM Partitioned LIS | ||
|---|---|---|---|---|
| LL (90% CI) | UL (90% CI) | LL (90% CI) | UL (90% CI) | |
| Creatinine (mmol/L) | ||||
| 1 to < 6 years | 19.4 (19.3, 19.6) | 41.9 (41.7, 42.0) | 17.5 (17.3, 17.7) | 49.6 (49.2, 50.3) |
| 6 to < 12 years | 28.5 (28.3, 28.6) | 55.8 (55.6, 56.0) | 26.5 (26.2, 26.7) | 66.3 (65.5, 67.0) |
| 12 to < 17 years boys | 38.0 (37.2, 38.5) | 73.4 (72.9, 74.4) | 39.6 (39.0, 40.1) | 83.9 (82.6, 84.8) |
| 12 to < 17 years girls | 35.1 (34.6, 35.6) | 69.2 (68.9, 69.6) | 30.3 (29.3, 31.2) | 83.5 (80.6, 87.4) |
| Urea (mmol/L) | ||||
| 1 to < 17 years | 2.55 (2.53, 2.56) | 6.05 (6.03, 6.06) | 2.45 (2.43, 2.47) | 5.93 (5.91, 5.97) |
LIS Laboratory Information System, GMM Gaussian Mixture Model, SOM Self-Organizing Map, LL lower limit, UL upper limit, CI confidence interval