Table 2.

Distribution of peripheral lymphocyte subpopulation in different cohort

	Benign(n = 44)	Borderline(n = 14)	Malignant(n = 112)	P
CD3+ T cells (%)	70.06 ± 8.27	69.33 ± 7.76	67.15 ± 9.49	P1 = 0.769* P2 = 0.075* P3 = 0.825*
CD3+CD4+T cells (%)	38.09 ± 7.00	37.00 ± 12.42	38.59 ± 9.05	P1 = 0.680* P2 = 0.738* P3 = 0.552*
CD3+CD8+ T cells (%)	30.91 ± 9.90	29.50 ± 7.03	26.84 ± 9.33	P1 = 0.624* P2 = 0.017* P3 = 0.307*
CD8+CD28+ T cells (%)	9.39 ± 3.00	11.15 ± 7.74	7.31 ± 2.77	P1 = 0.176* P2 < 0.001* P3 = 0.054*
NK cells (CD3−CD56+) (%)	16.03 ± 7.46	18.72 ± 8.42	18.10 ± 9.06	P1 = 0.259* P2 = 0.179* P3 = 0.810*
Tregs (CD4+CD25+CD127−)(%)	11.82 ± 2.23	13.96 ± 2.89	13.05 ± 3.22	P1 = 0.005* P2 = 0.021* P3 = 0.317*
B cells (CD19+) (%)	12.27 ± 5.13	10.56 ± 5.91	12.64 ± 5.28	P1 = 0.299* P2 = 0.689* P3 = 0.172*
CD4/CD8 ratio	1.42 ± 0.71	1.37 ± 0.56	1.78 ± 1.37	P1 = 0.478# P2 = 0.038# P3 = 0.274#

^aNumbers were presented as mean ± standard deviation

^bP values with statistical significance were denoted. P1 = Borderline Vs. Benign;P2 = Malignant Vs. Benign; P3 = Malignant Vs. Borderline

^*Paired T test

^#Mann–Whitney U test