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. 2007 Apr 18;2007(2):CD006003. doi: 10.1002/14651858.CD006003.pub2

Adloff 1987.

Methods Randomised clinical trial
Generation of the allocation sequence: unclear.
Allocation concealment: adequate. Sealed box.
Blinding: none (inadequate).
Follow‐up: adequate.
Intention‐to‐treat analysis: no.
Sample size calculation: no.
Participants Country: France. 
 Number randomised: 200. 
 Mean age: 49.9 years. 
 Females: 164.
Inclusion criteria: 
 Elective cholecystectomy.
Exclusion criteria: 
 CBD exploration.
Interventions Participants were randomly assigned to two groups.
Group 1: closed passive drain (n = 100). 
 Group 2: no drain (n = 100).
Co‐interventions:
Drain brought through: separate wound.
Antibiotic use: not stated.
Duration of drain: not stated.
Outcomes The main outcome measures were wound infection, chest infection, and hospital stay.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate