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. Author manuscript; available in PMC: 2022 Apr 11.
Published in final edited form as: J Clin Epidemiol. 2021 Mar 28;137:45–57. doi: 10.1016/j.jclinepi.2021.03.021

Table 3.

Prevalence of reporting as pragmatic trial and trial registration (Data source: MEDLINE N = 4337).

Item N (%)
Identification as pragmatic trial
Self-identification as “pragmatic”:
Anywhere (title, abstract or main text) 964 (22.2%)
 In title or abstract 534 (12.3%)
 In main text only (not in title or abstract)) 430 (9.9%)
Identification as pragmatic by NLM
 Pragmatic Clinical Trial as Publication type * 268 (6.2%)
 Pragmatic Clinical Trials as Topic * 22 (0.5%)
Trial registration
Registration indicated anywhere in text 3386 (78.1%)
 In abstract (n = 3386) 1991 (58.8%)
 In full text only (n = 3386) 1395 (41.2%)
Registration not reported 952 (21.9%)
Trial Registry, if registered ** (n = 3386)
ClinicalTrials.gov 1988 (58.7%)
 ISRCTN 660 (19.5%)
 ANZCTR 286 (8.4%)
 Other registry only 466 (13.8%)
*

As per December 2, 2020.

**

Trials may be registered in multiple registries, so does not sum to 3386.