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. Author manuscript; available in PMC: 2022 Apr 11.
Published in final edited form as: J Clin Epidemiol. 2021 Mar 28;137:45–57. doi: 10.1016/j.jclinepi.2021.03.021

Table 5.

Planned and actual accrual data in registry (Data Source: ClinicalTrials.gov, N = 1988).

Accrual data Descriptive summary
Target enrolment/anticipated enrolment *
 Min, Max 30, 800000
 Median (Q1–Q3) 440 (224–1200)
 Frequency Missing 91
Actual enrolment *
 Min, Max 60, 933789
 Median (Q1–Q3) 413.5 (216.25–1146.50)
 Frequency Missing 268
Accrual Ratio (actual/target enrolment) *
 Min, Max 0.1, 4.8
 Median (Q1–Q3) 1.0 (0.9–1.0)
 Frequency Missing 306
Ratio thresholds (N = 1682) N (%)
 <0.5 (i.e., less than 50% of target enrolment achieved) 83 (4.9%)
 0.5 to <0.85 274 (16.3%)
 0.85 to <1.15 1082 (64.3%)
 1.15 to <1.5 141 (8.4%)
 ≥1.5 (i.e., more than 150% of target enrolment achieved) 102 (6.1%)
*

Extreme outliers that were clearly erroneous have been set to missing.