Table 4.

ME/Kg/Dose of opioids prescribed to pediatric patients who received opioids before intervention and at 1 year after intervention.

	PreAdjusted Mean(95% CI)	1 YearAdjusted Mean(95% CI)	Adjusted Ratio(95% CI)	P Value	R[2]
Site 1	0.16 (0.14–0.19)	0.14 (0.12–0.16)	0.85 (0.75–0.98)	0.04	0.57
Site 2 *	0.13 *	NA**	NA	–	–
Site 3	0.19 (0.10–0.35)	0.18 (0.09–0.38)	0.97 (0.46–2.03)	0.93	0.36
Site 4	0.13 (0.07–0.27)	0.17 (0.12–0.25)	1.29 (0.87–1.90)	0.25	0.62
Site 5	0.15 (0.13–0.18)	0.12 (0.10–0.15)	0.80 (0.65–0.98)	0.04	0.57
Site 6 *	0.13 *	NA**	NA	–	–
Site 7	0.15 (0.13–0.17)	0.18 (0.14–0.22)	1.21 (0.97–1.51)	0.10	0.62
Site 8	0.12 (0.10–0.15)	0.18 (0.14–0.24)	1.47 (1.12–1.94)	0.01	0.57
Site 9	0.48 (0.34–0.67)	0.75 (0.47–1.18)	1.57 (0.99–2.48)	0.08	0.62
Overall	0.17 (0.14–0.22)	0.18 (0.16–0.20)	1.07 (0.95–1.19)	0.25	0.46

^*Adjusted means not estimable owing to either zero or 100% of patients receiving opioids in one of groups, here the mean was used instead.

^**No patients received opioids in these groups.