Table 2.
MR-PRESSO for causal effect between vitamin D and AF.
| Exposure | Model | Raw estimates | Outlier corrected estimates | Distortion test | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| nSNP | Beta | OR (95%CI) | P-value | nSNP | Beta | OR (95%CI) | P-value | P-value | ||
| Vitamin D | Model 1 | 53 | 0.039 | 1.040 (0.954,1.133) | 0.368 | 50 | 0.05 | 1.051(0.978,1.130) | 0.173 | 0.741 |
| Model 2 | 48 | 0.021 | 1.021 (0.942,1.107) | 0.613 | 47 | 0.03 | 1.031(0.958,1.108) | 0.422 | 0.812 | |
| 25-hydroxyvitamin D | Model 1 | 6 | 0.005 | 1.005 (0.842,1.199) | 0.958 | 6 | NA | NA | NA | NA |
| Model 2 | 5 | 0.019 | 1.019 (0.846,1.226) | 0.853 | 5 | NA | NA | NA | NA | |
AF, atrial fibrillation; SNP, single-nucleotide polymorphisms; OR, odds ratio.