Table 4.
Univariate and multivariate analyses of parameters associated with overall survival.
| Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|
| Parameter | HR | 95% CI | p Value | HR | 95 % CI | p Value |
| Male gender | 1.609 | 0.555–4.662 | 0.381 | |||
| Age < 65 years | 0.645 | 0.302–1.380 | 0.259 | |||
| Viral Hepatitis | 0.612 | 0.258–1.449 | 0.264 | |||
| BCLC AB | 0.632 | 0.276–1.445 | 0.277 | |||
| AFP < 400 ng/mL | 0.928 | 0.402–2.142 | 0.861 | |||
| ALBI score 1 | 0.043 | 0.005–0.337 | 0.003 | |||
| Child Pugh A | 0.152 | 0.045–0.515 | 0.002 | 0.112 | 0.024–0.534 | 0.006 |
| Extrahepatic spread of HCC | 2.182 | 0.996–4.780 | 0.051 | |||
| Prior local therapy/surgery | 0.450 | 0.205–0.988 | 0.047 | 0.346 | 0.122–0.978 | 0.045 |
Abbreviations: HR, hazard ratio; CI, confidence interval; BCLC stage AB. Barcelona Clinic Liver Cancer stage A and B; AFP, alpha-fetoprotein, ALBI score, albumin–bilirubin score.