Table 1.
Correlations of PD-L1 and CD8 status with clinicopathological parameters.
| Factors | n | CD8all High |
CD8all Low |
p-Value | CD8int High |
CD8int Low |
p-Value | n | CPS ≥ 1 | CPS < 1 | p-Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| pT | 0.033 | 0.001 | 0.015 | ||||||||
| T1 | 45 (11%) |
20 (44.4%) | 25 (55.5%) | 29 (64.4%) | 16 (35.6%) | 48 (11.7%) | 16 (33.3%) | 32 (66.7%) | |||
| T2 | 54 (13.3%) |
36 (66.7%) | 18 (33.3%) | 37 (68.5%) | 17 (31.5%) | 55 (13.5%) | 28 (50.9%) | 27 (49.1%) | |||
| T3 | 146 (35.9%) | 80 (54.8%) | 66 (45.2%) | 87 (59.6%) | 59 (40.4%) | 144 (35.3%) | 54 (37.5%) | 90 (62.5%) | |||
| T4 | 162 (39.8%) | 71 (43.8%) | 91 (56.2%) | 65 (40.1%) | 97 (59.9%) | 161 (39.5%) | 44 (27.3%) | 117 (72.7%) | |||
| pN | 0.37 | 0.045 | 0.112 | ||||||||
| N0 | 112 (27.5%) | 61 (54.5%) | 51 (45.5%) | 69 (61.6%) | 43 (38.4%) | 112 (27.8%) | 46 (41.1%) | 66 (58.9%) | |||
| N1-3 | 295 (72.5%) | 146 (49.5%) | 149 (50.5%) | 149 (50.5%) | 146 (49.5%) | 291 (72.2%) | 95 (32.6%) | 196 (67.4%) | |||
| Grading | 0.278 | 0.107 | 0.041 | ||||||||
| G1 | 21 (5.2%) |
8 (38.1%) |
13 (61.9%) | 14 (66.6%) | 7 (33.3%) |
23 (5.6%) |
8 (34.8%) |
15 (65.2%) | |||
| G2 | 96 (23.6%) | 45 (46.9%) | 51 (53.1%) | 58 (60.4%) | 38 (39.6%) | 97 (23.8%) | 44 (45.4%) | 53 (54.6%) | |||
| G3 | 290 (71.2%) | 154 (53.1%) | 136 (46.9%) | 146 (50.3%) | 144 (49.7%) | 288 (70.6%) | 90 (31.3%) | 198 (68.7%) | |||
| Laurén | 0.933 | 0.022 | <0.001 | ||||||||
| Intestinal | 207 (50.9%) | 102 (49.3%) | 105 (50.7%) | 125 (60.4%) | 82 (39.6%) | 211 (51.7%) | 101 (47.9%) | 110 (52.1%) | |||
| Diffuse | 131 (32.2%) | 69 (52.7%) | 62 (47.3%) | 58 (44.3%) | 73 (55.7%) | 127 (31.1%) | 22 (17.3%) | 105 (82.7%) | |||
| Mixed | 65 (16%) |
34 (52.3%) | 31 (47.7%) | 32 (49.2%) | 33 (50.8%) | 66 (16.2%) | 16 (24.2%) | 50 (75.8%) | |||
| Indeterm. | 4 (0.9%) |
2 (50%) |
2 (50%) |
3 (75%) |
1 (25%) |
4 (1%) |
3 (75%) |
1 (25%) |