Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 23;14(7):1625. doi: 10.3390/cancers14071625

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

KEGG and Gene Ontology (DIANA-mirPath) and dbEMT database analyses indicate modulations of EMT and metastasis-regulated genes by miRNAs in Akt1-deficient PC3 and DU145 cells. (A,B) Volcano plot showing highly modulated, EMT regulating miRNAs in Akt1-deficient PC3 and DU145 cells compared to Akt1 intact controls. (C,D) Chart showing predicted and known targets of the identified miRNAs from NanoString analysis of Akt1-deficient PC3 and DU145 cells indicating their predominant involvement in the regulation of EMT and metastasis. Only changes in the miRNA that are statistically significant (p < 0.05) are shown (n = 3).