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. 2022 Mar 23;14(7):1625. doi: 10.3390/cancers14071625

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Nanostring analysis, indicating modulations in EMT and metastasis regulating mRNAs in Akt1-deficient PC3 and DU145 cells. (A,B) Volcano plot showing highly modulated, EMT regulating mRNAs in Akt1-deficient PC3 and DU145 cells compared to Akt1 intact controls. (C) Bar graph showing mRNAs identified to be modulated by Akt1 deficiency in PC3 and DU145 cells compared to the predicted and known targets from dbEMT analysis. Only changes in the mRNA that are statistically significant (p < 0.05) are shown (n = 3).