Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Timeline of SNA preclinical and clinical development. First-generation SNA architectures focused on gene-regulation and the delivery of chemotherapeutic and imaging agents. Second generation SNAs are liposomal structures designed to active anti-tumor immune responses. Next-generation SNAs are multimodal structures, functionalized with multiple therapeutic cues. Bcl2L12, Bcl2Like12; TMZ, temozolomide; TLR, Toll-like receptor; TNBC, triple negative breast cancer.
