ADCC |
Antibody-dependent cytotoxicity |
AML |
Acute myeloid leukemia |
APC |
Antigen-presenting cell |
B7-H3 |
B7 homolog 3 |
BCL |
B-cell chronic lymphocytic leukemia/lymphoma |
BTLA |
B- and T-cell attenuator |
CAF |
Cancer-associated fibroblast |
Ceacam-1 |
Carcinoembryonic antigen related cell adhesion molecules 1 |
CRC |
Colorectal cancer |
CTL |
Cytotoxic T lymphocyte |
CTLA-4 |
Cytotoxic T lymphocyte associated protein |
DC |
Dendritic cell |
EGF |
Epidermal growth factor |
FGL1 |
Fibrinogen-like protein 1 |
HCC |
Hepatocellular carcinoma |
HMGB1 |
High mobility group protein B1 |
HVEM |
Herpes virus entry mediator |
IC |
Immune checkpoint protein |
ICI |
Immune checkpoint inhibitor |
ICOS |
Inducible T cell costimulatory |
IDO |
Indoleamine-2,3-dioxygenase |
IFN |
Interferon |
IGFL |
Insulin growth factor-like family member |
IL |
Interleukin |
ILC |
Innate lymphoid cells |
iNOS |
Inducible nitric oxide |
irAE |
Immune-related adverse event |
LAG-3 |
lymphocyte activation gene 3 |
LPS |
Lipopolysaccharide |
MAPK |
Mitogen-activated protein kinase |
MDSC |
Myeloid-derived suppressor cell |
MHC |
Major histocompatibility complex |
NF-κB |
Nuclear factor kappa B |
NK |
Natural killer |
NKT |
NK T cell |
NSCLC |
Non-small-cell lung cancer |
ORR |
Objective response rate |
OS |
Overall survival |
PD-1 |
Programmed cell death |
PD-L1 |
PD-1 ligand 1 |
pDC |
Plasmacytoid DC |
PI3K |
Phosphoinositide 3-kinases |
PFS |
Progression-free survival |
PS |
Phosphatidyl serine |
PSGL-1 |
P-selectin glycoprotein ligand-1 |
PTEN |
Phosphatase and tensin homolog |
STAT |
Signal transducer and activator of transcription |
TAA |
tumor-associated antigen |
TAM |
Tumor-associated macrophage |
TGF-β |
tumor growth factor-β |
TIGIT |
T cell Immunoglobulin [Ig] and immune receptor tyrosine-based inhibitory motif domain |
TIM-3 |
T cell Ig and mucin domain 3 |
Tfh |
T follicular helper cell |
TIL |
Tumor-infiltrating leukocyte |
TLR |
Toll-like receptor |
TLT-2 |
Triggering receptor expressed on myeloid cells-like transcript 2 |
TME |
Tumor microenvironment |
TNF |
Tumor necrosis factor |
Treg |
Regulatory T cell |
VEGF |
Vascular endothelial growth factor |
VISTA |
V-set immunoregulatory receptor |
VSGL3 |
V-Set and Immunoglobulin domain containing 3 |