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. 2022 Mar 29;14(7):1734. doi: 10.3390/cancers14071734

Table 2.

Multivariate analysis of factors influencing survival in R/R-AML patients treated with venetoclax.

Variable Median (Days) P-Univariate P-Multivariate HR (95% CI)
Total, n = 47 78
Age
<65 y, n = 17 34 0.919 0.326 1.48 (0.68–3.22)
≥65 y, n = 34 34
Sex
Female, n = 18 131 0.217 0.010 3.37 (1.45–7.82)
Male, n = 33 78
ECOG performance status
0, n = 10 NR 0.001 0.005 14.96 (1.91–117.21)
≥1, n = 40 75
ORR (CR + CRi + PR)
Yes,11 215 0.004 0.002 6.13 (0.68–3.22)
No, 37 69

Abbreviations: CR, complete remission; CRi, CR with incomplete blood count recovery; ECOG, Eastern Cooperative Oncology Group scale; PR, partial response; R/R-AML, relapsed/refractory acute myeloid leukemia.