Table 1.
Characteristics of the training and validation cohorts.
| Variable | Training Cohort (n = 279) | Validation Cohort (n = 77) | ||||
|---|---|---|---|---|---|---|
| n | Mean or % | SD | n | Mean or % | SD | |
| Clinical center | ||||||
| Berlin | 70 | 25% | 0 | 0% | ||
| Freiburg | 72 | 26% | 0 | 0% | ||
| Innsbruck | 0 | 0% | 38 | 49% | ||
| Leuven | 0 | 0% | 39 | 51% | ||
| Vienna | 137 | 49% | 0 | 0% | ||
| Menopausal status | ||||||
| <50 years | 95 | 34.1% | 27 | 35.1% | ||
| ≥50 years | 184 | 65.9% | 50 | 64.9% | ||
| CA125 | ||||||
| <35 U/mL | 116 | 42% | 38 | 49% | ||
| ≥35 U/mL | 163 | 58% | 39 | 51% | ||
| Age (years) | 279 | 55.2 | 15.6 | 77 | 56.3 | 15.6 |
| CA125 (U/mL) | 279 | 444.8 | 751.5 | 77 | 341.6 | 690.3 |
| HE4 (pg/mL) | 279 | 28,051 | 107,318.9 | 77 | 15,987.4 | 35,499 |
| OPN (pg/mL) | 279 | 48,120.4 | 81,244.2 | 77 | 41,656.3 | 33,348.7 |
| PRL (pg/mL) | 279 | 47,622.9 | 78,443.3 | 77 | 25,950.3 | 36,547.4 |
| MIF (pg/mL) | 279 | 1788.2 | 2256.9 | 77 | 146.8 | 147.5 |
| Leptin (pg/mL) | 279 | 19,381.6 | 24,482.9 | 77 | 22,090.3 | 24,032.8 |