Table 3.

Measures of diagnostic accuracy broken down by age (cutoff 50 years).

	Proteomic Model 2021		Combined Model 2021		Full Combined Model 2021
	Age < 50	Age ≥ 50	Age < 50	Age ≥ 50	Age < 50	Age ≥ 50
Patient number	27	50	27	50	27	50
C-index (95% CI)	0.58 (0.23–0.93)	0.95 (0.9–1.0)	0.57 (0.22–0.92)	0.95 (0.89–1.0)	0.51 (0.17–0.86)	0.96 (0.91–1.0)
Threshold	0.18	0.34	0.09	0.57	0.17	0.59
Overall accuracy	0.81	0.92	0.81	0.94	0.78	0.96
Sensitivity	0.57	0.90	0.57	0.92	0.43	0.95
Specificity	0.90	1.00	0.90	1.00	0.90	1.00
PPV	0.67	1.00	0.67	1.00	0.60	1.00
NPV	0.86	0.71	0.86	0.77	0.82	0.83