Table 4.

Diagnostic performance broken down by CA125 (cutoff 35 U/mL).

	Proteomic Model 2021		Combined Model 2021		Full Combined Model 2021
	Normal	Elevated	Normal	Elevated	Normal	Elevated
Patient number	38	39	38	39	38	39
C-index (95% CI)	0.51 (0.27–0.75)	0.74 (0.43–1.0)	0.59 (0.33–0.84)	0.87 (0.73–1.0)	0.67 (0.43–0.91)	0.88 (0.71–1.0)
Threshold	0.09	0.85	0.71	0.92	0.60	0.87
Overall accuracy	0.74	0.82	0.82	0.79	0.82	0.74
Sensitivity	0.36	0.83	0.45	0.78	0.55	0.72
Specificity	0.89	0.67	0.96	1.00	0.93	1.00
PPV	0.57	0.97	0.83	1.00	0.75	1.00
NPV	0.77	0.25	0.81	0.27	0.83	0.23