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. 2022 Mar 28;14(7):1711. doi: 10.3390/cancers14071711

Table 4.

Mean training and validation scores for the best performing machine learning models using the 1.5 times mean liver SUV thresholding segmentation technique.

Machine Learning Model Hyperparameters Features AUC Mean Training AUC Mean Validation
SUVmax/130
Ridge Regression C: 1 × 10−5, penalty: l2, solver: saga Stage Four, Age, PET original GLDM Large Dependence Low Grey Level Emphasis, PET original GLSZM Large Area High Grey Level Emphasis 0.74 (0.03) 0.71 (0.09)
Support Vector Machine C: 1, gamma: 0.43727367418726576, kernel: rbf PET square 10th Percentile, PET square first order Energy 0.78 (0.02) 0.73 (0.07)
Random Forest bootstrap: True, max depth: 10, max features: sqrt, min samples leaf: 33, min samples split: 5, n estimators: 90 Age, PET original shape Elongation, PET original shape Least Axis Length, PET original shape Major Axis Length, PET original shape Maximum 2D Diameter Column, PET original shape Mesh Volume
SUVmax/64
Ridge Regression C: 1.0, penalty: l2, solver: liblinear Stage Three, Age, PET wavelet-LHL GLCM Imc1, PET square GLDM Dependence Variance, PET square GLSZM Small Area Low Grey Level Emphasis 0.76 (0.02) 0.73 (0.07)
Support Vector Machine C: 1, gamma: 0.43727367418726576, kernel: rbf PET square first order 10 Percentile, PET square first order Energy 0.78 (0.02) 0.73 (0.07)
Random Forest bootstrap: True, max depth: 10, max features: log2, min samples leaf: 42, min samples split: 6, n estimators: 237 PET original shape Sphericity, PET original GLSZM Large Area Emphasis 0.70 (0.02) 0.69 (0.07)

l2 = Ridge regression penalty, liblinear = A library for large linear classification, GLSZM = grey level size zone matrix, GLDM = grey level dependence matrix, lbp-3D-m1 = local binary pattern filtered image at level 1, lbp-3D-k = local binary pattern kurtosis image, GLCM = grey level co-occurrence matrix, rbf = radial basis function.