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Cytoskeletal elements regulate PI3K/AKT signaling cascade. The three types of cytoskeleton collectively control the PI3K/AKT pathway. The cytoskeleton and its associated proteins play critical roles in regulating multiple steps and players of the PI3K/AKT signaling pathway, including signaling molecule recruitment, antagonist sequestration, and regulation of gene expression. Image created with BioRender.com (accessed on 14 February 2022).
