Table 1.
Site-related pathogens and genetic mutations.
| EMZL Site-Related Genomic Aberrations, Pathogens, Autoimmune Disorders | ||
|---|---|---|
| Localization | Genomic Aberrations | Pathogens/Autoimmune Disorders |
| Gastric MALT | Trisomy: +3, +18 |
Helicobacter pylori
Helicobacter Heimanni |
| IGH/MALT1 t(14;18)(q32;q21) BIRC3/MALT1 t(11;18)(q21;q21) BCL10/IGH t(1;14)(p22;q32) | ||
| Intestine | Trisomy: +3, +18 | Campylobacter jejuni |
| BIRC3/MALT1 t(11;18)(q21;q21) BCL10/IGH t(1;14)(p22;q32) | ||
| Skin | Trisomy: +3, +18 | Borrelia burgdorferi |
| IGH/MALT1 t(14;18)(q32;q21) | ||
| FOXP1/IGH t(3;14)(p14.1;q32) | ||
| Ocular Adnexa | Trisomy: +3, +18 |
Chlamydia psittaci
Sjogren’s syndrome |
| IGH/MALT1 t(14;18)(q32;q21) | ||
| FOXP1/IGH t(3;14)(p14.1;q32) | ||
| TNFAIP3 target mutation | ||
| Lung | Trisomy: +3, +18 |
Achromobacter xylosoxidans
Lymphocytic interstitial pneumonia |
| BIRC3/MALT1 t(11;18)(q21;q21) | ||
| Salivary Gland | Trisomy: +3, +18 IGH/MALT1 t(14;18)(q32;q21) |
Sjogren’s syndrome
Hepatitis C virus |
| TBL1XR1 target mutation | ||
| GPR34 target mutation | ||