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. Author manuscript; available in PMC: 2022 Dec 15.
Published in final edited form as: Cancer. 2021 Aug 20;127(24):4602–4612. doi: 10.1002/cncr.33861

TABLE 3.

ORs for the Associations of State-Based nSES Quartiles With Breast Cancer Subtypes Relative to LumA (n = 5547)

State-Based nSES Quartilea
Q4 (Reference) Q3 Q2 Q1 P for Trend
LumA (2723) 1229 849 464 181
LumB (n = 1856) 743 610 384 119
 OR, age-adjustedb 1.00 1.19 1.37 1.09 .002
  95% CI 1.03–1.38 1.17–1.61 0.83–1.43
 OR, model 1c 1.00 1.17 1.30 1.02 .024
  95% CI 1.01–1.36 1.11–1.53 0.78–1.35
 OR, model 2d 1.00 1.17 1.31 1.03 .031
  95% CI 1.01–1.37 1.11–1.55 0.77–1.37
 Q statistice 0.28
 P .597
Her2-e (n = 267) 102 95 47 23
 OR, age-adjustedb 1.00 1.35 1.24 1.59 .032
  95% CI 1.02–1.78 0.87–1.77 0.99–2.54
 OR, model 1c 1.00 1.33 1.16 1.39 .168
  95% CI 1–1.77 0.8–1.68 0.82–2.38
 OR, model 2d 1.00 1.27 1.08 1.27 .405
  95% CI 0.95–1.71 0.73–1.61 0.74–2.21
 Q statistice 1.06
 P .303
TNBC (n = 701) 261 214 163 63
 OR, age-adjustedb 1.00 1.17 1.65 1.63 <.001
  95% CI 0.96–1.42 1.32–2.05 1.13–2.34
 OR, model 1c 1.00 1.07 1.41 1.18 .017
  95% CI 0.88–1.31 1.13–1.76 0.83–1.68
 OR, model 2d 1.00 1.05 1.35 1.09 .087
  95% CI 0.86–1.29 1.06–1.71 0.76–1.56
 Q statistice 0.16
 P .684

Abbreviations: AJCC, American Joint Committee on Cancer; CI, confidence interval; Her2-e, Her2-enriched; LACE, Life After Cancer Epidemiology; LumA, luminal A; LumB, luminal B; nSES, neighborhood-level socioeconomic status; OR, odds ratio; Q1, quartile 1; Q2, quartile 2; Q3, quartile 3; Q4, quartile 4; SES, socioeconomic status; TNBC, triple-negative breast cancer.

a

For each censal year, quartiles were created on the basis of the state distribution of nSES at the census block group level and then were applied to the addresses of the women in the cohort.

b

Adjusted for age at diagnosis.

c

Model 1 adjusted for possible confounders, including age at diagnosis (continuous), race (non-Latina White, Black, Latina, Asian, or other), nativity (US-born or foreign-born), AJCC stage (I, II, III, or IV), days from diagnosis to baseline measures (<52, 52–75, 76–519, or ≥520), and study (LACE or Pathways).

d

Model 2 adjusted for variables in model 1 plus individual education and individual income.

e

The Q statistic was calculated for model 2 with a continuous variable for days from diagnosis to study enrollment and a recategorized stage variable in which stages II, III, and IV were collapsed into 1 level (given differences in study recruitment).