TABLE 1.
Epidemiological, clinical, and laboratory features in the 88 patients with culture-confirmed enteric fever
| Patient characteristics | Treatment
|
|
|---|---|---|
| Ofloxacin (n = 44) | Azithromycin (n = 44) | |
| No. of males/no. of females | 26/18 | 20/24 |
| Mean age (95% CI, range) (yr) | 24.7 (22.6–26.8, 15–40) | 26.6 (23.1–30.1, 15–68) |
| Mean wt (95% CI, range) (kg) | 48.7 (46.3–51.0, 29–62) | 47.3 (45.3–49.3, 34–60) |
| Mean duration of fever before admission (95% CI, range) (days) | 13.6 (11.4–15.8, 5–32) | 11.9 (10.4–13.3, 5–25) |
| Abdominal pain (n [%]) | 10 (23) | 8 (18) |
| Vomiting (n [%]) | 3 (7) | 8 (18) |
| Diarrhea (n [%]) | 34 (77) | 32 (73) |
| Hepatomegaly (n [%]) | 13 (30) | 9 (21) |
| Splenomegaly (n [%]) | 1 (2) | 3 (7) |
| Mean hematocrit (95% CI, range) (%) | 39 (37–41, 31–45) | 39 (37–41, 25–47) |
| Mean white cell count (95% CI, range) (109/liter) | 7.5 (6.1–8.9, 3.0–16.3) | 6.5 (5.5–7.5, 2.8–12.0) |
| Mean platelet count (95% CI, range) (109/liter) | 176 (156–196, 57–374) | 177 (162–192, 84–300) |
| Organism isolated from blood sample | 43/1 | 43/1 |
| MDR strains (n [%]) | 35 (80) | 33 (77) |
| Nalidixic acid-resistant strains (n [%]) | 21 (48) | 25 (57) |
| Positive pretreatment fecal cultures (n [%]) | 12 (27) | 12 (27) |