Figure 1.

Scheme illustrating different platelet functions in the immune response. Platelets sense and bind invading bacteria and injured endothelium, resulting in platelet activation. Upon activation, platelets release chemokines and cytokines such as RANTES, triggering leukocyte recruitment and PMVs acting on gene expression of monocytes and monocyte (MC)-derived cells such as dendritic cells (DC). In addition, neutrophils are attracted, and NET formation occurs at the site of infection via platelet-dependent mechanisms. Created with BioRender.com (accessed on 21 March 2022).