Table 3.
Population effect of genetic testing for patients with BC.
| IMPACT | Testing All BC Patients | Testing Based on Family History | No Testing | Difference (Testing All vs. No Testing) |
|||||
|---|---|---|---|---|---|---|---|---|---|
| Patients | Relatives | Patients | Relatives | Patients | Relatives | Patients | Relatives | Total | |
| Germline BC cases | 2075 a | 7658 | 3806 a | 10,493 | 4515 a | 11,576 | 2440 | 3918 | 6358 |
| Germline OC cases | 737 | 2144 | 1263 | 2640 | 1487 | 2904 | 750 | 760 | 1510 |
| Germline BC/OC deaths | 4873 | 3679 | 7237 | 4968 | 8247 | 5469 | 3374 | 1790 | 5164 |
a Indicates contralateral breast cancer cases in patients with unilateral breast cancer (breast cancer in one breast). This table depicts the additional BC and OC cases and deaths prevented by an unselected BC testing strategy.