Table 1.
The distributions of demographical characteristics and clinical parameters in 284 controls and 284 cases with OSCC.
| Variable | Controls (N = 284) | Patients (N = 284) | p-Value |
|---|---|---|---|
| Age (years) Mean ± SD (Median) |
53.74 ± 7.73 (53) | 55.11 ± 10.30 (55) | p = 0.0742 |
| Betel nut chewing | |||
| No | 273 (96.1%) | 51 (18.0%) | p < 0.001 * |
| Yes | 11 (3.9%) | 233 (82%) | |
| Cigarette smoking | |||
| No | 262 (92.3%) | 33 (11.6%) | p < 0.001 * |
| Yes | 22 (7.7%) | 251 (88.4) | |
| Alcohol drinking | |||
| No | 277 (97.5%) | 139 (48.9) | p < 0.001 * |
| Yes | 7 (2.5%) | 145 (51.1) | |
| Stage | |||
| I + II | 168 (59.2) | ||
| III + IV | 116 (40.8) | ||
| Tumor T status | |||
| T1 + T2 | 193 (68.0%) | ||
| T3 + T4 | 91 (32.0%) | ||
| Lymph node status | |||
| N0 | 216 (76.1%) | ||
| N1 + N2 + N3 | 68 (23.9%) | ||
| Metastasis | |||
| M0 | 266 (93.7%) | ||
| M1 | 18 (6.3%) | ||
| Cell differentiation | |||
| Well-differentiated | 48 (16.9%) | ||
| Moderately or poorly differentiated | 236 (83.1) |
N: number. The Mann–Whitney U test was used between age of OSCC patients and cancer-free patients. The significance of betel nut chewing, cigarette smoking, and alcohol drinking between OSCC patients and cancer-free patients was calculated by logistic regression. * p-value < 0.05 is statistically significant.