Table 3.
Clinical statuses and KMT2C rs4725443 genotype frequencies in cases-of-OSCC group.
| Variable | KMT2C (rs4725443) | |||
|---|---|---|---|---|
| TT (%) (N = 180) |
TC + CC (%) (N = 104) |
OR (95% CI) | p-Value | |
| Clinical stage | ||||
| Stage I/II | 111 (61.7%) | 57 (54.8%) | 1.000 | p = 0.258 |
| Stage III/IV | 69 (38.3%) | 47 (45.2%) | 1.326 (0.813–2.164) | |
| Tumor size | ||||
| T1 + T2 | 126 (70.0%) | 67 (64.4%) | 1.000 | p = 0.332 |
| T3 + T4 | 54 (30.0%) | 37 (35.6%) | 1.289 (0.772–2.152) | |
| Lymph node metastasis | ||||
| No | 139 (77.2%) | 77 (74.0%) | 1.000 | p = 0.545 |
| Yes | 41 (22.8%) | 27 (26.0%) | 1.189 (0.679–2.081) | |
| Distant metastasis | ||||
| No | 169 (93.9%) | 97 (93.3%) | 1.000 | p = 0.836 |
| Yes | 11 (6.1%) | 7 (6.7%) | 1.109 (0.416–2.954) | |
| Cell differentiation | ||||
| Good | 28 (15.6%) | 20 (19.2%) | 1.000 | p = 0.427 |
| Moderate/poor | 152 (84.4%) | 84 (80.8%) | 0.774 (0.411–1.457) | |
N: number. The odds ratios (ORs) with their 95% confidence intervals were estimated by logistic regression models.