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Production of (a) IL-10, (b) IL-13, (c) IL-5, and (d) MIP-1b by activated PBMCs is inhibited in contact and non-contact (tw) co-cultures with MSCs. Data are shown as mean ± std; n = 5, t-test, * reliability of differences at p < 0.05. Contact refers to contact MSC–PBMC co-culture, tw refers to non-contact co-culture. Five unrelated donors per cell type were used.
