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. 2022 Mar 28;11(7):1146. doi: 10.3390/cells11071146

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Kisspeptin expression in arcuate nuclei. The changes in kisspeptin (KP) expression in females (black line) and males (green line) were traced through the neonatal/prepubertal periods, the pubertal period, and the adulthood in previous studies. There is a high degree of sexual dimorphism in KP expression in the arcuate (ARC) nuclei during neonatal and prepubertal period. The sex-specific dimorphic expression of KPs in ARC nuclei sustains until the onset of puberty when the levels of KP expression become similar.