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. 2022 Feb 23;79(5):1067–1078. doi: 10.1161/HYPERTENSIONAHA.121.18255

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© 2022 The Authors.

Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 3. — Subgroup analysis age in mean difference.

Total indicates number of participants. Some randomized controlled trials investigated the effect of 2 different therapies. ACE indicates angiotensin-converting enzyme; Ca, calcium blocker; CBF, cerebral blood flow; Diu, diuretic; In, intensive; IV, inverse variance; Nor, normal; and Stand, standard.