ACKR3	atypical chemokine receptor 3
Akt	protein kinase B
cAMP	cyclic adenosine monophosphate
AOM	azoxymethane
APC	adenomatous polyposis coli
ARE	AU-rich element
ChIP	chromatin immunoprecipitation
CIN	chromosome instability
CIMP	CpG island methylator phenotype
CpG	cytosine-phosphate-guanine
CRC	colorectal cancer
CTLA-4	cytotoxic T lymphocyte Antigen 4
CXCL-10/12	C-X-C motif ligand 10/12
CXCR-3/4/7	C-X-C motif receptor 3/4/7
CAF	cancer-associated fibroblasts
DSS	dextran sodium sulfate
ECM	extracellular matrix
EGFR	epidermal growth factor receptor
EMT	epithelial–mesenchymal transition
ERK	extracellular signal-regulated kinases
FAP	familial adenomatous polyposis
FGF	fibroblast growth factor
5-FU	5-fluorouracil
GAG	glycosaminoglycans
GEO	Gene Expression Omnibus
GRK2	G-protein-coupled receptor kinase 2
GTP	guanine–triphosphate
HDAC	histone deacetylases
HIC1	hypermethylated in cancer 1
HIF	hypoxia-inducible factor
HiRE	HIC1-responsive elements
HIV	human immunodeficiency virus
IBD	chronic inflammatory bowel disease
ICAM	intercellular adhesion molecule
ICI	immune checkpoint inhibitor
IGF	insulin-like growth factor
IL-2/6	interleukin-2/6
ITG	integrin
Jak	Janus kinase
JNK	c-Jun N-terminal kinase
Lgr5	leucine-rich repeat-containing G-protein coupled receptor 5
MAPK	mitogen-activated protein kinases
MDSCs	myeloid-derived suppressor cells
MMP	matrix metalloproteinase
MMR	mismatch Repair
MSC	mesenchymal stromal cells
MSS	microsatellite stability
MSI	microsatellite instability
mTOR	mammalian target of rapamycin
NF-κB	nuclear factor-kappa B
PCAF	P300/CBP-associated factor
PDGF	platelet-derived growth factor
PD-1	programmed cell death protein 1
PD-L1	programmed cell death protein ligand 1
PI3K	phosphatidylinositol 3-kinase
PLC	Phospholipase C
PPPC1	serine/threonine-protein phosphatase PP1-gamma catalytic
SDF-1	stromal-cell-derived factor 1
α-SMA	alpha-smooth muscle actin
STAT	signal transducer and activator of transcription
TAM	tumor associated macrophages
TCGA	the cancer genome atlas program
TGF	tumor growth factor
TIC	tumor-initiating cell
TIMP	tissue inhibitor of metalloproteinases
TNF	tumor necrosis factor
TNM	tumor, node, metastasis
TTP	tristetraprolin
UTR	untranslated transcribed region
VEGF	vascular endothelial growth factor