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Serum levels of GM193663 (top panel), GM211676 (middle panel), and GM237354 (bottom panel) in uninfected mice given either a single oral 50-mg/kg dose or 19 daily oral doses of 100 mg/kg/day. Serum levels were determined by bioassay, which had a lower limit of detectable drug concentration for each of these compounds of 2.5 μg/ml.
